CCNT2

Across TCGA cell cohorts, CCNT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,705 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCNT2-associated GO terms across cancer lineages are Positive regulation of double-strand break repair, Regulation of mRNA splicing, via spliceosome, and Regulation of DNA repair. Each is linked with CCNT2 in more than 19 cancer types. Because this analysis shows association rather than direction, both CCNT2-to-partner and partner-to-CCNT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of double-strand break repair grouped by CCNT2-low versus CCNT2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNT2→partner) and Y-score (partner→CCNT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Positive regulation of double-strand break repair →	+0.101	+1.079	<.001	<.001	3	20
SOFT_TISSUE	Regulation of mRNA splicing, via spliceosome →	+0.104	+1.204	<.001	<.001	3	19
LUNG_SCLC	Regulation of DNA repair →	+0.084	+1.285	<.001	<.001	3	19
STOMACH	Heterochromatin organization →	+0.074	+0.750	.004	.006	3	19
BONE	Late viral transcription →	+0.137	+0.793	<.001	<.001	3	19
BREAST	Regulation of double-strand break repair →	+0.068	+0.895	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,705 associations by consensus.

Positive regulation of double-strand break repair by CCNT2 expression — LUNG_SCLC

Explore this box plot interactively →