CCNT2

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CCNT2 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CCNT2-associated genes across cancer lineages are R3HDML, BANF2, and CST9. Each is linked with CCNT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCNT2-to-partner and partner-to-CCNT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, R3HDML grouped by CCNT2-low versus CCNT2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNT2→partner) and Y-score (partner→CCNT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaR3HDML →+0.006+5.209<.001.00531
BLOOD_LymphomaBANF2 →+0.047+5.643<.001.00231
BLOOD_LymphomaCST9 →+0.060+5.209<.001.00531
BLOOD_LymphomaCYLC1 →+0.029+4.867<.001.00931
BLOOD_LymphomaC18orf63 →+0.012+4.867<.001.00931
LUNG_NSCLC_LUADTMEM244 →+0.079+4.189<.001.00231
Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

R3HDML by CCNT2 expression — BLOOD_Lymphoma

Box plot of R3HDML in CCNT2-low vs CCNT2-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration