Across TCGA pan-cancer cohorts, CCNQP3 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of CCNQP3’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where CCNQP3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CCNQP3 is over-expressed in tumor, although a few such as STAD show the opposite, repressed pattern.
COAD, LUAD, and STAD are the cancer types where CCNQP3 tumor–normal differential expression is most reproducible.