CCNQ

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CCNQ protein abundance is significantly associated with the RNA expression of many other genes, with 1,669 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCNQ-associated genes across cancer lineages are PCNX4, HABP2, and CD109. Each is linked with CCNQ in more than 1 cancer types. Because this analysis shows association rather than direction, both CCNQ-to-partner and partner-to-CCNQ results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCNQ versus PCNX4 in UCEC, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNQ→partner) and Y-score (partner→CCNQ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECPCNX4 →+0.475+1.509.002<.00132
LUADHABP2 →+2.325+0.797<.001<.00132
UCECCD109 →+2.547+2.185<.001<.00132
UCECIFTAP →+0.624+1.686.001<.00132
UCECULK4 →+0.656+1.284.002.00132
UCECSNTB1 →+1.161+1.596.008.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,669 associations by consensus.

CCNQ vs PCNX4 — UCEC

Per-sample scatter of CCNQ vs PCNX4 in UCEC (Pearson r = 0.57).

Explore this scatter interactively →

Exploration