CCNQ

Across TCGA cell cohorts, CCNQ RNA expression is significantly associated with the go_rna of many other GO terms, with 3,073 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCNQ-associated GO terms across cancer lineages are snRNA pseudouridine synthesis, Positive regulation of telomerase RNA localization to Cajal body, and Mitotic spindle midzone assembly. Each is linked with CCNQ in more than 14 cancer types. Because this analysis shows association rather than direction, both CCNQ-to-partner and partner-to-CCNQ results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, snRNA pseudouridine synthesis grouped by CCNQ-low versus CCNQ-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNQ→partner) and Y-score (partner→CCNQ) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	snRNA pseudouridine synthesis →	+0.134	+1.072	<.001	<.001	3	15
OESOPHAGUS	Positive regulation of telomerase RNA localization to Cajal body →	+0.113	+0.989	.002	<.001	3	12
URINARY_TRACT	Mitotic spindle midzone assembly →	+0.217	+0.692	<.001	<.001	3	11
URINARY_TRACT	Mitotic spindle elongation →	+0.217	+0.692	<.001	<.001	3	11
PANCREAS	DNA geometric change →	+0.118	+1.039	.001	<.001	3	10
URINARY_TRACT	Spindle midzone assembly →	+0.213	+0.526	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,073 associations by consensus.

snRNA pseudouridine synthesis by CCNQ expression — BONE

Explore this box plot interactively →