CCNP

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CCNP RNA expression is significantly associated with the protein abundance of many other proteins, with 11,066 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CCNP-associated proteins across cancer lineages are ZNRD2, PAFAH1B3, and DIAPH2. Each is linked with CCNP in more than 3 cancer types. Because this analysis shows association rather than direction, both CCNP-to-partner and partner-to-CCNP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCNP versus ZNRD2 in LSCC, with a Pearson correlation of 0.28.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNP→partner) and Y-score (partner→CCNP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCZNRD2 →+0.281+0.395<.001.00534
BRCAPAFAH1B3 →+0.466+1.394<.001<.00134
GBMDIAPH2 →-0.238-0.538.001<.00133
GBMTRIM28_S697 →+0.699+0.565<.001<.00133
GBMVCPIP1_S757 →+0.427+0.594<.001<.00133
BRCABAZ2A_S1770 →+0.747+1.286<.001<.00133
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,066 associations by consensus.

CCNP vs ZNRD2 — LSCC

Per-sample scatter of CCNP vs ZNRD2 in LSCC (Pearson r = 0.28).

Explore this scatter interactively →

Exploration