CCNP

Across TCGA patient cohorts, CCNP protein abundance is significantly associated with the RNA expression of many other genes, with 1,594 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CCNP-associated genes across cancer lineages are SPECC1L, LRP5L, and FBXO7. Each is linked with CCNP in more than 1 cancer types. Because this analysis shows association rather than direction, both CCNP-to-partner and partner-to-CCNP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCNP versus SPECC1L in HNSC, with a Pearson correlation of -0.39.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNP→partner) and Y-score (partner→CCNP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SPECC1L →	-0.433	-1.361	.006	.001	3	1
HNSC	LRP5L →	-0.967	-1.631	.002	<.001	3	1
HNSC	FBXO7 →	-0.458	-1.135	.006	.003	3	1
HNSC	DNAL4 →	-0.868	-1.300	.001	.001	3	1
HNSC	ZBED4 →	-0.577	-1.606	<.001	<.001	3	1
HNSC	RBM23 →	-0.532	-1.305	.009	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,594 associations by consensus.

CCNP vs SPECC1L — HNSC

Explore this scatter interactively →