CCNP

Across TCGA cell cohorts, CCNP RNA expression is significantly associated with the go_rna of many other GO terms, with 3,366 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible CCNP-associated GO terms across cancer lineages are Regulation of myoblast fusion, Negative regulation of myoblast fusion, and Cilium movement. Each is linked with CCNP in more than 9 cancer types. Because this analysis shows association rather than direction, both CCNP-to-partner and partner-to-CCNP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of myoblast fusion grouped by CCNP-low versus CCNP-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNP→partner) and Y-score (partner→CCNP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Regulation of myoblast fusion →	+0.103	+1.979	<.001	<.001	3	10
LUNG_SCLC	Negative regulation of myoblast fusion →	+0.104	+1.525	<.001	.004	3	9
CNS	Cilium movement →	-0.053	-0.274	<.001	.001	3	9
LUNG_SCLC	Negative regulation of syncytium formation by plasma membrane fusion →	+0.104	+1.740	<.001	<.001	3	9
LUNG_SCLC	Regulation of syncytium formation by plasma membrane fusion →	+0.110	+1.819	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Negative regulation of macroautophagy →	+0.074	+0.470	<.001	.005	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,366 associations by consensus.

Regulation of myoblast fusion by CCNP expression — LUNG_SCLC

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