Across TCGA cell cohorts, CCNL2 mutation is significantly associated with the RNA expression of many other genes, with 18 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCNL2-associated genes across cancer lineages are TAAR5, OR4D6, and RD3L. Each is linked with CCNL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCNL2-to-partner and partner-to-CCNL2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNL2→partner) and Y-score (partner→CCNL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	TAAR5 →	+0.056	+5.807	<.001	.001	3	1
OVARY	OR4D6 →	+0.016	+5.807	<.001	.001	3	1
LUNG_SCLC	RD3L →	+0.032	+5.029	<.001	.006	3	1
LUNG_NSCLC_LUAD	RXFP2 →	+0.054	+4.544	<.001	.003	3	1
LUNG_NSCLC_LUAD	UBQLN3 →	+0.011	+4.734	<.001	.002	3	1
LUNG_NSCLC_LUAD	MRGPRG →	+0.029	+4.544	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 18 associations by consensus.

Exploration

CCNL2 survival (RNA) · tumor vs normal (RNA) · all CCNL2 data types