Across TCGA pan-cancer cohorts, CCNJP1 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of CCNJP1’s most consistent transcriptional readouts.
The strongest signal is observed in lung squamous cell carcinoma (LUSC), where CCNJP1 RNA is repressed in tumor relative to normal tissue. In most cancer types CCNJP1 is over-expressed in tumor, although a few such as LUSC show the opposite, repressed pattern.
LUSC and HNSC are the cancer types where CCNJP1 tumor–normal differential expression is most reproducible.