CCNJL

Across TCGA patient cohorts, CCNJL mutation is significantly associated with the total protein of many other genes, with 45 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCNJL-associated genes across cancer lineages are FOXO3a_pS318_S321, JNK2, and MEK1. Each is linked with CCNJL in more than 1 cancer types. Because this analysis shows association rather than direction, both CCNJL-to-partner and partner-to-CCNJL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FOXO3a_pS318_S321 grouped by CCNJL-low versus CCNJL-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNJL→partner) and Y-score (partner→CCNJL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FOXO3a_pS318_S321 →	-0.111	-1.668	.011	.021	3	2
UCEC	JNK2 →	+0.303	+2.000	<.001	.003	3	2
UCEC	MEK1 →	+0.493	+3.807	<.001	<.001	3	2
UCEC	PEA-15_pS116 →	+0.333	+2.584	.007	.010	3	2
UCEC	Src_pY527 →	-0.362	-2.115	.017	.016	3	2
UCEC	TFRC →	+0.407	+2.584	.030	.010	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 45 associations by consensus.

FOXO3a_pS318_S321 by CCNJL expression — UCEC

Explore this box plot interactively →