CCNJL

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CCNJL mutation is significantly associated with the RNA expression of many other genes, with 9 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCNJL-associated genes across cancer lineages are MMP26, OR10W1, and OR10Q1. Each is linked with CCNJL in more than 1 cancer types. Because this analysis shows association rather than direction, both CCNJL-to-partner and partner-to-CCNJL results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MMP26 grouped by CCNJL-low versus CCNJL-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNJL→partner) and Y-score (partner→CCNJL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEMMP26 →+0.033+3.217<.001.00631
LARGE_INTESTINEOR10W1 →+0.014+3.562<.001.00231
LARGE_INTESTINEOR10Q1 →+0.088+3.242.002.00331
BLOOD_LymphomaC11orf97 →+2.125+5.209<.001.00531
BLOOD_LeukemiaSVOP →+0.030+3.771.006.00431
BLOOD_LeukemiaRNF186 →+0.082+3.450<.001.00431
Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

MMP26 by CCNJL expression — LARGE_INTESTINE

Box plot of MMP26 in CCNJL-low vs CCNJL-high samples in LARGE_INTESTINE.

Explore this box plot interactively →

Exploration