CCNH

Across TCGA pan-cancer cohorts, CCNH Mutation is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CCNH data layer compared with 27 for mass-spec protein and 6 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher CCNH Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated CCNH expression acts as an unfavorable survival marker, although some lineages such as UCEC and BLCA show a favorable association.

OV, HNSC, and UCEC are the cancer types where CCNH Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	OS	Median	II,III,IV	0.291	0.692	.022	36	view →
HNSC	OS	Median	All	0.156	0.710	.002	24	view →
UCEC	DFS	Median	All	1.000	0.621	.011	24	view →
LUSC	OS	Median	All	0.011	0.819	<.001	12	view →
BLCA	OS	Median	III,IV	1.000	0.532	.040	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CCNH–OV (OS)

Open the OV breakdown →