CCNH

Across TCGA pan-cancer cohorts, CCNH mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated CCNH data layer compared with 27 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher CCNH mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CCNH expression acts as an unfavorable survival marker, although some lineages such as LUAD and LSCC show a favorable association.

HNSC, CCRCC, and LUAD are the cancer types where CCNH mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Median	All	0.380	1.000	.008	27	view →
CCRCC	OS	Median	All	0.840	0.948	.014	11	view →
LUAD	DFS	Median	II,III,IV	0.962	0.711	.013	10	view →
LSCC	DFS	Tertile	II,III,IV	0.939	0.537	.004	10	view →
PDAC	DFS	Tertile	IV	0.217	0.550	.024	3	view →
GBM	DFS	Quartile	All	0.532	0.245	.047	2	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

CCNH–HNSC (OS)

Open the HNSC breakdown →