CCNH

Across TCGA patient cohorts, CCNH protein abundance is significantly associated with the RNA expression of many other genes, with 10,700 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCNH-associated genes across cancer lineages are KIF18A, PCNA, and CCNB1. Each is linked with CCNH in more than 6 cancer types. Because this analysis shows association rather than direction, both CCNH-to-partner and partner-to-CCNH results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCNH versus KIF18A in BRCA, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNH→partner) and Y-score (partner→CCNH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	KIF18A →	+0.841	+0.256	<.001	<.001	3	7
HNSC	PCNA →	+0.930	+0.202	.009	.001	2	7
LUAD	CCNB1 →	+0.901	+0.141	<.001	.001	3	6
OV	DHFR →	+0.903	+0.449	<.001	<.001	3	6
HNSC	KNSTRN →	+0.703	+0.184	.008	.004	3	6
GBM	HELLS →	+0.811	+0.234	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,700 associations by consensus.

CCNH vs KIF18A — BRCA

Explore this scatter interactively →