CCNG2

Across TCGA patient cohorts, CCNG2 mutation is significantly associated with the total protein of many other genes, with 4 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCNG2-associated genes across cancer lineages are VHL, Caspase-8, and EGFR_pY1173. Each is linked with CCNG2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCNG2-to-partner and partner-to-CCNG2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, VHL grouped by CCNG2-low versus CCNG2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNG2→partner) and Y-score (partner→CCNG2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	VHL →	-1.247	-3.321	<.001	.010	3	1
UCEC	Caspase-8 →	-0.292	-3.321	.026	.010	2	1
UCEC	EGFR_pY1173 →	+0.110	+3.348	.008	.005	1	1
UCEC	S6_pS240_S244 →	+0.420	+3.321	.048	.010	1	1

Each partner links to its Q-omics profile. Showing the 4 strongest of 4 associations by consensus.

VHL by CCNG2 expression — UCEC

Explore this box plot interactively →