CCNG1

Across TCGA patient cohorts, CCNG1 mutation is significantly associated with the total protein of many other genes, with 34 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCNG1-associated genes across cancer lineages are 14-3-3_beta, EGFR_pY1068, and eIF4E. Each is linked with CCNG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCNG1-to-partner and partner-to-CCNG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 14-3-3_beta grouped by CCNG1-low versus CCNG1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNG1→partner) and Y-score (partner→CCNG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.093	-2.558	.016	.010	3	1
UCEC	EGFR_pY1068 →	-0.246	-2.087	.010	.005	3	1
UCEC	eIF4E →	+0.216	+3.584	.007	.002	3	1
UCEC	A-Raf_pS299 →	-0.114	-1.700	.012	.042	3	1
UCEC	GATA6 →	-0.149	-1.899	.016	.016	3	1
UCEC	ACVRL1 →	-0.111	-2.680	.033	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 34 associations by consensus.

14-3-3_beta by CCNG1 expression — UCEC

Explore this box plot interactively →