CCNF

Across TCGA pan-cancer cohorts, CCNF Mutation is linked to patient survival in 9 of 34 cancer types, making it a survival-associated CCNF data layer compared with 28 for mass-spec protein.

The strongest signal is observed in ovarian serous cystadenocarcinoma (OV), where higher CCNF Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated CCNF expression acts as an unfavorable survival marker.

OV, KIRC, and LGG are the cancer types where CCNF Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
OV	DFS	Median	All	0.104	0.541	<.001	18	view →
KIRC	DFS	Median	All	0.062	0.865	<.001	18	view →
LGG	OS	Median	All	0.147	0.799	<.001	6	view →
PRAD	DFS	Median	All	0.617	0.886	.027	6	view →
ACC	DFS	Median	All	0.195	0.748	.003	6	view →
UCEC	OS	Median	IV	0.231	0.592	.036	6	view →
SKCM	DFS	Median	III,IV	0.145	0.661	.002	5	view →
SARC	DFS	Median	All	0.179	0.594	.031	3	view →
LUSC	DFS	Median	II,III,IV	0.199	0.748	.006	3	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

CCNF–OV (DFS)

Open the OV breakdown →