CCNE1

Across TCGA patient cohorts, CCNE1 protein abundance is significantly associated with the protein abundance of many other proteins, with 5,174 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCNE1-associated proteins across cancer lineages are CCNE1_S387, CCNE1_S103, and BPTF_S763. Each is linked with CCNE1 in more than 4 cancer types. Because this analysis shows association rather than direction, both CCNE1-to-partner and partner-to-CCNE1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCNE1 versus CCNE1_S387 in LUAD, with a Pearson correlation of 0.74.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNE1→partner) and Y-score (partner→CCNE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CCNE1_S387 →	+1.861	+1.100	.002	.009	1	5
LSCC	CCNE1_S103 →	+1.717	+1.199	<.001	<.001	3	3
LSCC	BPTF_S763 →	+0.721	+0.809	.002	.001	3	2
LSCC	BPTF_T610 →	+0.970	+1.316	.001	<.001	3	2
UCEC	BUB1B →	+0.688	+0.412	<.001	<.001	3	2
LSCC	BYSL →	+0.410	+0.664	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,174 associations by consensus.

CCNE1 vs CCNE1_S387 — LUAD

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