CCNE1

Across TCGA cell cohorts, CCNE1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible CCNE1-associated genes across cancer lineages are PTCRA, OR6J1, and OPN1MW. Each is linked with CCNE1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCNE1-to-partner and partner-to-CCNE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PTCRA grouped by CCNE1-low versus CCNE1-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNE1→partner) and Y-score (partner→CCNE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	PTCRA →	+0.056	+4.523	<.001	.003	3	1
LUNG_SCLC	OR6J1 →	+0.019	+4.044	.005	.009	3	1
LUNG_SCLC	OPN1MW →	+0.027	+4.643	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

PTCRA by CCNE1 expression — LUNG_SCLC

Explore this box plot interactively →