CCNDBP1

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, CCNDBP1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CCNDBP1 data layer compared with 23 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher CCNDBP1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated CCNDBP1 expression acts as an unfavorable survival marker, although some lineages such as HNSC show a favorable association.

HNSC, CCRCC, and LUAD are the cancer types where CCNDBP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
HNSCOSTertileII,III,IV0.9460.783.01020view →
CCRCCDFSQuartileIII,IV0.2970.802.00311view →
LUADOSTertileII,III,IV0.4080.809.0198view →
GBMDFSTertileAll0.6230.821.0185view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CCNDBP1–HNSC (OS)

Kaplan–Meier survival curve for CCNDBP1 mass-spec protein-high vs -low samples in HNSC.

Open the HNSC breakdown →

Exploration