CCNDBP1

Across TCGA patient cohorts, CCNDBP1 mutation is significantly associated with the total protein of many other genes, with 17 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCNDBP1-associated genes across cancer lineages are EGFR, FOXO3a, and JNK_pT183_Y185. Each is linked with CCNDBP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCNDBP1-to-partner and partner-to-CCNDBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR grouped by CCNDBP1-low versus CCNDBP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNDBP1→partner) and Y-score (partner→CCNDBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR →	-0.232	-3.321	<.001	.010	3	1
UCEC	FOXO3a →	+0.111	+1.598	.012	.044	3	1
UCEC	JNK_pT183_Y185 →	-0.195	-2.000	.008	.030	3	1
UCEC	Ku80 →	+0.215	+1.598	.037	.044	3	1
UCEC	MEK1 →	+0.408	+2.807	.010	.003	3	1
UCEC	mTOR_pS2448 →	-0.129	-2.439	.048	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 17 associations by consensus.

EGFR by CCNDBP1 expression — UCEC

Explore this box plot interactively →