CCND2

Across TCGA patient cohorts, CCND2 mutation is significantly associated with the RNA expression of many other genes, with 4,662 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCND2-associated genes across cancer lineages are RN7SL97P, GUF1, and LPCAT1. Each is linked with CCND2 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCND2-to-partner and partner-to-CCND2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL97P grouped by CCND2-low versus CCND2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCND2→partner) and Y-score (partner→CCND2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL97P →	+0.106	+1.933	<.001	<.001	3	3
UCEC	GUF1 →	+0.472	+2.420	<.001	<.001	3	2
UCEC	LPCAT1 →	+0.357	+1.470	.008	<.001	3	2
UCEC	GTF3C6 →	+0.412	+1.828	<.001	<.001	3	2
UCEC	BUB1B →	+0.586	+1.844	<.001	<.001	3	2
UCEC	DFFA →	+0.355	+1.884	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,662 associations by consensus.

RN7SL97P by CCND2 expression — UCEC

Explore this box plot interactively →