CCND2

Across TCGA cell cohorts, CCND2 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCND2-associated genes across cancer lineages are FAM236A and OR52H1. Each is linked with CCND2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCND2-to-partner and partner-to-CCND2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FAM236A grouped by CCND2-low versus CCND2-high in UPPER_AERODIGESTIVE_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCND2→partner) and Y-score (partner→CCND2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	FAM236A →	+0.120	+5.357	<.001	.003	3	1
LARGE_INTESTINE	OR52H1 →	+0.020	+3.347	.003	.005	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

FAM236A by CCND2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →