CCND2-AS1

Across TCGA pan-cancer cohorts, CCND2-AS1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of CCND2-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where CCND2-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types CCND2-AS1 is over-expressed in tumor, although a few such as LUAD and UCEC show the opposite, repressed pattern.

LUAD, UCEC, and BLCA are the cancer types where CCND2-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CCND2-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Male	III,IV	−0.615	<.001	11	view →
UCEC	All	All	−1.150	<.001	8	view →
BLCA	Male	IV	−0.794	.007	7	view →
BRCA	All	All	−0.518	<.001	6	view →
LUSC	All	All	−0.260	<.001	6	view →
KIRP	All	All	+0.577	<.001	3	view →
KICH	All	All	−0.229	.004	3	view →
PRAD	All	All	−0.287	<.001	2	view →
COAD	Male	All	−0.234	.017	2	view →
READ	All	II,III,IV	−0.542	.023	1	view →
CHOL	Male	All	+0.166	.049	1	view →
HNSC	Male	III,IV	+0.150	.046	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

CCND2-AS1–LUAD

Open the LUAD breakdown →