CCND1

Across TCGA pan-cancer cohorts, CCND1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated CCND1 data layer compared with 22 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CCND1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CCND1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and PDAC show a favorable association.

CCRCC, LSCC, and PDAC are the cancer types where CCND1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	III,IV	0.985	0.067	.008	24	view →
LSCC	OS	Quartile	All	0.819	0.966	.004	11	view →
PDAC	DFS	Tertile	II,III,IV	0.589	0.286	.035	4	view →
UCEC	OS	Tertile	All	1.000	0.831	.037	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

CCND1–CCRCC (DFS)

Open the CCRCC breakdown →