CCND1

Across TCGA patient cohorts, CCND1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,805 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CCND1-associated proteins across cancer lineages are PPFIA1, BCAR1, and PTPN2_S304. Each is linked with CCND1 in more than 3 cancer types. Because this analysis shows association rather than direction, both CCND1-to-partner and partner-to-CCND1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCND1 versus PPFIA1 in HNSC, with a Pearson correlation of 0.62.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCND1→partner) and Y-score (partner→CCND1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PPFIA1 →	+0.744	+1.648	<.001	<.001	3	4
UCEC	BCAR1 →	+0.241	+1.087	.001	<.001	3	4
UCEC	PTPN2_S304 →	-0.622	-0.759	.004	.009	3	3
PDAC	PLOD1 →	+0.409	+0.607	<.001	<.001	3	3
PDAC	PLOD2 →	+0.648	+0.579	<.001	<.001	3	3
BRCA	ARL3 →	+0.507	+1.329	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,805 associations by consensus.

CCND1 vs PPFIA1 — HNSC

Explore this scatter interactively →