CCND1

Across TCGA patient cohorts, CCND1 mutation is significantly associated with the RNA expression of many other genes, with 845 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCND1-associated genes across cancer lineages are RN7SL847P, RNU6-990P, and MTCYBP45. Each is linked with CCND1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCND1-to-partner and partner-to-CCND1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL847P grouped by CCND1-low versus CCND1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCND1→partner) and Y-score (partner→CCND1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL847P →	+0.273	+5.010	<.001	.009	3	2
LUAD	RNU6-990P →	+1.188	+6.333	<.001	<.001	3	2
LUAD	MTCYBP45 →	+0.082	+5.739	<.001	.001	3	2
LUAD	RPL7P54 →	+0.094	+4.293	.003	.008	3	2
LUAD	MRGPRX13P →	+0.361	+4.631	<.001	.008	3	2
LGG	OR11H2 →	+0.057	+6.491	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 845 associations by consensus.

RN7SL847P by CCND1 expression — CESC

Explore this box plot interactively →