CCND1

Across TCGA cell cohorts, CCND1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,701 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCND1-associated GO terms across cancer lineages are Cellular response to environmental stimulus, Cellular response to abiotic stimulus, and Response to corticosterone. Each is linked with CCND1 in more than 10 cancer types. Because this analysis shows association rather than direction, both CCND1-to-partner and partner-to-CCND1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cellular response to environmental stimulus grouped by CCND1-low versus CCND1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCND1→partner) and Y-score (partner→CCND1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Cellular response to environmental stimulus →	+0.053	+1.921	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Cellular response to abiotic stimulus →	+0.053	+1.891	.005	<.001	2	11
BREAST	Response to corticosterone →	+0.235	+1.939	<.001	<.001	3	10
LARGE_INTESTINE	Release of cytochrome c from mitochondria →	+0.118	+2.160	<.001	<.001	3	10
BREAST	Positive regulation of ubiquitin-dependent protein catabolic process →	+0.064	+1.938	<.001	.005	3	9
UPPER_AERODIGESTIVE_TRACT	Regulation of miRNA metabolic process →	+0.083	+1.728	<.001	.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,701 associations by consensus.

Cellular response to environmental stimulus by CCND1 expression — LARGE_INTESTINE

Explore this box plot interactively →