CCNC

Across TCGA patient cohorts, CCNC protein abundance is significantly associated with the RNA expression of many other genes, with 10,836 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCNC-associated genes across cancer lineages are METAP2, TAF1B, and EID3. Each is linked with CCNC in more than 2 cancer types. Because this analysis shows association rather than direction, both CCNC-to-partner and partner-to-CCNC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCNC versus METAP2 in PDAC, with a Pearson correlation of 0.89.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNC→partner) and Y-score (partner→CCNC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	METAP2 →	+0.500	+0.500	.003	.007	3	3
LSCC	TAF1B →	+0.454	+0.244	<.001	<.001	3	3
LSCC	EID3 →	+1.363	+0.364	<.001	<.001	3	3
GBM	SLC6A1 →	-1.395	-0.267	.001	.003	3	3
GBM	NTM →	-1.319	-0.307	<.001	<.001	3	3
BRCA	INPP4B →	-1.017	-0.358	.003	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,836 associations by consensus.

CCNC vs METAP2 — PDAC

Explore this scatter interactively →