CCNC

Across TCGA cell cohorts, CCNC RNA expression is significantly associated with the go_rna of many other GO terms, with 2,524 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCNC-associated GO terms across cancer lineages are 7-methylguanosine RNA capping, 7-methylguanosine mRNA capping, and Spermidine biosynthetic process. Each is linked with CCNC in more than 14 cancer types. Because this analysis shows association rather than direction, both CCNC-to-partner and partner-to-CCNC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 7-methylguanosine RNA capping grouped by CCNC-low versus CCNC-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNC→partner) and Y-score (partner→CCNC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	7-methylguanosine RNA capping →	+0.121	+0.769	<.001	.001	3	15
OVARY	7-methylguanosine mRNA capping →	+0.121	+0.769	<.001	.001	3	15
OVARY	Spermidine biosynthetic process →	+0.142	+0.796	<.001	<.001	3	14
BONE	Glutaminyl-tRNAGln biosynthesis via transamidation →	+0.092	+0.554	<.001	.004	3	13
UPPER_AERODIGESTIVE_TRACT	Spermine biosynthetic process →	+0.146	+0.705	.006	.007	3	13
BREAST	Regulation of mitochondrial transcription →	+0.113	+0.553	<.001	.008	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,524 associations by consensus.

7-methylguanosine RNA capping by CCNC expression — OVARY

Explore this box plot interactively →