CCNC

Across TCGA cell cohorts, CCNC mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible CCNC-associated genes across cancer lineages are USP29, OR9G4, and RNASE9. Each is linked with CCNC in more than 1 cancer types. Because this analysis shows association rather than direction, both CCNC-to-partner and partner-to-CCNC results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, USP29 grouped by CCNC-low versus CCNC-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNC→partner) and Y-score (partner→CCNC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	USP29 →	+0.016	+5.662	<.001	.002	3	1
LUNG_NSCLC_LUAD	OR9G4 →	+0.039	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	RNASE9 →	+0.022	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	KRTAP10-3 →	+0.032	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	GAGE12D →	+2.651	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	GAGE12C →	+1.371	+5.228	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

USP29 by CCNC expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →