CCNB2

Across TCGA patient cohorts, CCNB2 mutation is significantly associated with the RNA expression of many other genes, with 691 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCNB2-associated genes across cancer lineages are RN7SL275P, RNY4P18, and TOMM22. Each is linked with CCNB2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCNB2-to-partner and partner-to-CCNB2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL275P grouped by CCNB2-low versus CCNB2-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNB2→partner) and Y-score (partner→CCNB2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RN7SL275P →	+0.167	+5.351	<.001	.001	3	2
UCEC	RNY4P18 →	+0.262	+3.123	.001	.006	3	2
UCEC	TOMM22 →	+0.462	+3.491	.005	.002	3	1
UCEC	PHF5A →	+0.555	+3.516	.001	.002	3	1
UCEC	POLR3H →	+0.393	+3.467	.006	.002	3	1
UCEC	TRMU →	+0.477	+3.353	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 691 associations by consensus.

RN7SL275P by CCNB2 expression — SKCM

Explore this box plot interactively →