CCNB1IP1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CCNB1IP1 mutation is significantly associated with the RNA expression of many other genes, with 377 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCNB1IP1-associated genes across cancer lineages are RNA5SP422, RN7SKP59, and RNA5SP413. Each is linked with CCNB1IP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCNB1IP1-to-partner and partner-to-CCNB1IP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP422 grouped by CCNB1IP1-low versus CCNB1IP1-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNB1IP1→partner) and Y-score (partner→CCNB1IP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADRNA5SP422 →+0.216+5.070.001.00432
UCECRN7SKP59 →+0.093+2.961<.001.00332
UCECRNA5SP413 →+0.778+2.084.006.00632
UCECRNA5SP420 →+0.445+2.382.006.00332
UCECRN7SL386P →+0.118+2.599.006.00332
CESCLINC02559 →+1.780+6.342<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 377 associations by consensus.

RNA5SP422 by CCNB1IP1 expression — STAD

Box plot of RNA5SP422 in CCNB1IP1-low vs CCNB1IP1-high samples in STAD.

Explore this box plot interactively →

Exploration