CCNA2

Across TCGA pan-cancer cohorts, CCNA2 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated CCNA2 data layer compared with 31 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher CCNA2 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CCNA2 expression acts as an unfavorable survival marker, although some lineages such as LUAD and UCEC show a favorable association.

CCRCC, LUAD, and HNSC are the cancer types where CCNA2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Median	II,III,IV	0.486	1.000	.008	20	view →
LUAD	DFS	Tertile	III,IV	0.920	0.405	.010	13	view →
HNSC	OS	Quartile	All	0.121	1.000	.038	12	view →
UCEC	OS	Tertile	III,IV	1.000	0.328	.024	8	view →
PDAC	DFS	Tertile	II,III,IV	0.312	0.972	.024	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

CCNA2–CCRCC (OS)

Open the CCRCC breakdown →