CCNA2

Across TCGA cell cohorts, CCNA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,456 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCNA2-associated GO terms across cancer lineages are Regulation of mitotic sister chromatid separation, Mitotic nuclear division, and Regulation of metaphase/anaphase transition of cell cycle. Each is linked with CCNA2 in more than 19 cancer types. Because this analysis shows association rather than direction, both CCNA2-to-partner and partner-to-CCNA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mitotic sister chromatid separation grouped by CCNA2-low versus CCNA2-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCNA2→partner) and Y-score (partner→CCNA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Regulation of mitotic sister chromatid separation →	+0.254	+1.471	<.001	<.001	3	20
BONE	Mitotic nuclear division →	+0.135	+1.588	.003	.003	3	20
OESOPHAGUS	Regulation of metaphase/anaphase transition of cell cycle →	+0.183	+1.432	<.001	.001	3	20
OESOPHAGUS	Regulation of mitotic spindle checkpoint →	+0.176	+1.612	<.001	<.001	3	20
OESOPHAGUS	Regulation of chromosome separation →	+0.261	+1.427	<.001	<.001	3	20
UPPER_AERODIGESTIVE_TRACT	Positive regulation of chromosome separation →	+0.225	+1.420	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,456 associations by consensus.

Regulation of mitotic sister chromatid separation by CCNA2 expression — OESOPHAGUS

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