CCNA1

Across TCGA pan-cancer cohorts, CCNA1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated CCNA1 data layer compared with 23 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher CCNA1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated CCNA1 expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.

LUAD, PDAC, and LSCC are the cancer types where CCNA1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Quartile	III,IV	0.166	0.753	.010	22	view →
PDAC	OS	Median	II,III,IV	0.859	0.204	.042	6	view →
LSCC	DFS	Quartile	All	0.837	1.000	.020	5	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

CCNA1–LUAD (OS)

Open the LUAD breakdown →