CCN6

Across TCGA patient cohorts, CCN6 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,092 significant associations in total. PRAD shows the largest number of these associations.

The most reproducible CCN6-associated GO terms across cancer lineages are Macromolecule deacylation, Obsolete regulation of dosage compensation by inactivation of X chromosome, and Protein localization to nucleoplasm. Each is linked with CCN6 in more than 15 cancer types. Because this analysis shows association rather than direction, both CCN6-to-partner and partner-to-CCN6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Macromolecule deacylation grouped by CCN6-low versus CCN6-high in UVM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCN6→partner) and Y-score (partner→CCN6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	Macromolecule deacylation →	+0.049	+0.151	<.001	<.001	3	16
UVM	Obsolete regulation of dosage compensation by inactivation of X chromosome →	+0.074	+0.158	<.001	<.001	3	15
UVM	Protein localization to nucleoplasm →	+0.049	+0.148	<.001	<.001	3	14
UVM	Tubulin deacetylation →	+0.052	+0.152	<.001	<.001	3	14
UVM	RNA surveillance →	+0.058	+0.166	<.001	<.001	3	14
UVM	Nuclear RNA surveillance →	+0.061	+0.139	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,092 associations by consensus.

Macromolecule deacylation by CCN6 expression — UVM

Explore this box plot interactively →