CCN4

Across TCGA patient cohorts, CCN4 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,228 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCN4-associated proteins across cancer lineages are P3H1, P3H3, and PCOLCE. Each is linked with CCN4 in more than 9 cancer types. Because this analysis shows association rather than direction, both CCN4-to-partner and partner-to-CCN4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCN4 versus P3H1 in BRCA, with a Pearson correlation of 0.64.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCN4→partner) and Y-score (partner→CCN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	P3H1 →	+0.707	+1.447	<.001	<.001	3	10
OV	P3H3 →	+0.791	+1.465	<.001	<.001	3	10
BRCA	PCOLCE →	+0.773	+1.457	<.001	<.001	3	10
GBM	RCN3 →	+0.879	+1.367	<.001	<.001	3	10
GBM	SERPINH1 →	+0.612	+1.492	<.001	<.001	3	10
UCEC	CALD1 →	+1.000	+0.920	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,228 associations by consensus.

CCN4 vs P3H1 — BRCA

Explore this scatter interactively →