CCN4

Across TCGA patient cohorts, CCN4 protein abundance is significantly associated with the RNA expression of many other genes, with 13,605 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CCN4-associated genes across cancer lineages are MXRA5, TNFAIP6, and POSTN. Each is linked with CCN4 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCN4-to-partner and partner-to-CCN4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCN4 versus MXRA5 in LUAD, with a Pearson correlation of 0.57.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCN4→partner) and Y-score (partner→CCN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	MXRA5 →	+1.844	+0.565	<.001	<.001	3	3
LUAD	TNFAIP6 →	+1.374	+0.637	<.001	<.001	3	3
GBM	POSTN →	+4.998	+0.936	<.001	<.001	3	3
BRCA	SFRP2 →	+2.276	+0.686	<.001	<.001	3	3
GBM	COL5A2 →	+2.131	+0.966	<.001	<.001	3	3
GBM	COL15A1 →	+1.978	+1.127	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,605 associations by consensus.

CCN4 vs MXRA5 — LUAD

Explore this scatter interactively →