CCN2

Across TCGA patient cohorts, CCN2 protein abundance is significantly associated with the RNA expression of many other genes, with 8,828 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible CCN2-associated genes across cancer lineages are MYL9, COL5A1, and TAGLN. Each is linked with CCN2 in more than 8 cancer types. Because this analysis shows association rather than direction, both CCN2-to-partner and partner-to-CCN2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCN2 versus MYL9 in OV, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCN2→partner) and Y-score (partner→CCN2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MYL9 →	+1.160	+0.769	<.001	.002	3	9
OV	COL5A1 →	+1.716	+0.661	<.001	<.001	3	9
OV	TAGLN →	+1.468	+0.701	<.001	<.001	3	9
COAD	SFRP4 →	+2.926	+1.091	.008	.002	2	9
CCRCC	LTBP2 →	+1.319	+0.640	<.001	<.001	3	8
UCEC	CNN1 →	+1.731	+0.448	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,828 associations by consensus.

CCN2 vs MYL9 — OV

Explore this scatter interactively →