CCN1

Across TCGA patient cohorts, CCN1 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,600 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCN1-associated proteins across cancer lineages are SVIL_S467, CALD1_S73, and ARHGEF17_S527. Each is linked with CCN1 in more than 9 cancer types. Because this analysis shows association rather than direction, both CCN1-to-partner and partner-to-CCN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCN1 versus SVIL_S467 in GBM, with a Pearson correlation of 0.43.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCN1→partner) and Y-score (partner→CCN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SVIL_S467 →	+1.126	+1.375	<.001	<.001	3	10
OV	CALD1_S73 →	+2.008	+1.777	.003	.002	3	10
LSCC	ARHGEF17_S527 →	+0.586	+0.936	<.001	<.001	3	9
GBM	PPP1R18_S195 →	+0.576	+1.481	<.001	<.001	3	9
GBM	PPP1R18_S224 →	+0.538	+1.545	<.001	<.001	3	9
GBM	PCOLCE →	+0.755	+1.099	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,600 associations by consensus.

CCN1 vs SVIL_S467 — GBM

Explore this scatter interactively →