CCN1

Across TCGA patient cohorts, CCN1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,236 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CCN1-associated genes across cancer lineages are SERPINE1, LOX, and PLAUR. Each is linked with CCN1 in more than 9 cancer types. Because this analysis shows association rather than direction, both CCN1-to-partner and partner-to-CCN1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCN1 versus SERPINE1 in COAD, with a Pearson correlation of 0.58.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCN1→partner) and Y-score (partner→CCN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SERPINE1 →	+1.749	+0.712	<.001	<.001	3	10
BRCA	LOX →	+1.447	+0.637	<.001	<.001	3	9
CCRCC	PLAUR →	+1.077	+0.448	<.001	.003	3	9
OV	FN1 →	+1.810	+0.514	<.001	<.001	3	9
OV	SNAI1 →	+0.843	+0.617	<.001	<.001	3	9
LSCC	CALU →	+0.701	+0.641	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,236 associations by consensus.

CCN1 vs SERPINE1 — COAD

Explore this scatter interactively →