CCL7

Across TCGA patient cohorts, CCL7 protein abundance is significantly associated with the RNA expression of many other genes, with 9,151 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CCL7-associated genes across cancer lineages are SHROOM1, SBK1, and MITF. Each is linked with CCL7 in more than 4 cancer types. Because this analysis shows association rather than direction, both CCL7-to-partner and partner-to-CCL7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCL7 versus SHROOM1 in BRCA, with a Pearson correlation of 0.88.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL7→partner) and Y-score (partner→CCL7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SHROOM1 →	+1.986	+0.828	<.001	<.001	3	5
GBM	SBK1 →	-1.077	-0.348	<.001	<.001	3	4
BRCA	MITF →	+0.712	+0.582	<.001	<.001	3	4
BRCA	PLAT →	+1.735	+0.638	<.001	<.001	3	3
BRCA	NCAM2 →	+0.927	+0.529	.003	<.001	3	3
UCEC	IFITM2 →	+0.709	+0.286	.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,151 associations by consensus.

CCL7 vs SHROOM1 — BRCA

Explore this scatter interactively →