CCL7

Across TCGA patient cohorts, CCL7 mutation is significantly associated with the total protein of many other genes, with 35 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCL7-associated genes across cancer lineages are PCNA, GAPDH, and eEF2. Each is linked with CCL7 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCL7-to-partner and partner-to-CCL7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PCNA grouped by CCL7-low versus CCL7-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL7→partner) and Y-score (partner→CCL7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PCNA →	+0.250	+2.222	.006	.011	3	3
UCEC	GAPDH →	+0.454	+1.700	.046	.044	3	2
UCEC	eEF2 →	+0.342	+2.999	.024	.035	3	1
UCEC	A-Raf_pS299 →	-0.144	-3.169	.004	.019	3	1
UCEC	ERK2 →	+0.236	+2.321	.003	.033	3	1
UCEC	FoxM1 →	+0.284	+2.222	.009	.011	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

PCNA by CCL7 expression — UCEC

Explore this box plot interactively →