CCL7

Across TCGA cell cohorts, CCL7 RNA expression is significantly associated with the go_rna of many other GO terms, with 930 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible CCL7-associated GO terms across cancer lineages are Regulation of natural killer cell chemotaxis, Regulation of viral process, and Negative regulation of lymphocyte chemotaxis. Each is linked with CCL7 in more than 7 cancer types. Because this analysis shows association rather than direction, both CCL7-to-partner and partner-to-CCL7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of natural killer cell chemotaxis grouped by CCL7-low versus CCL7-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL7→partner) and Y-score (partner→CCL7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of natural killer cell chemotaxis →	+1.394	+0.271	<.001	.004	2	8
SOFT_TISSUE	Regulation of viral process →	+0.083	+0.740	<.001	.002	3	5
SKIN	Negative regulation of lymphocyte chemotaxis →	+1.471	+0.177	<.001	<.001	3	5
LUNG_NSCLC_LUAD	Actin filament fragmentation →	+0.091	+0.112	<.001	.009	3	5
SOFT_TISSUE	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment →	+0.154	+1.062	.001	.001	3	4
SOFT_TISSUE	T cell selection →	+0.078	+0.568	.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 930 associations by consensus.

Regulation of natural killer cell chemotaxis by CCL7 expression — OVARY

Explore this box plot interactively →