CCL4L2

Across TCGA patient cohorts, CCL4L2 mutation is significantly associated with the RNA expression of many other genes, with 247 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCL4L2-associated genes across cancer lineages are OR5H7P, NIPA2P3, and SIRPD. Each is linked with CCL4L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCL4L2-to-partner and partner-to-CCL4L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR5H7P grouped by CCL4L2-low versus CCL4L2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL4L2→partner) and Y-score (partner→CCL4L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	OR5H7P →	+0.123	+4.464	<.001	.005	3	2
UCEC	NIPA2P3 →	+0.143	+3.997	<.001	.009	3	2
UCEC	SIRPD →	+0.148	+2.960	<.001	.007	3	1
UCEC	SLCO1B1 →	+0.572	+2.876	<.001	.008	3	1
UCEC	IL21 →	+0.290	+2.763	<.001	.009	3	1
UCEC	LINC02536 →	+0.132	+3.997	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 247 associations by consensus.

OR5H7P by CCL4L2 expression — UCEC

Explore this box plot interactively →