CCL4L2

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CCL4L2 mutation is significantly associated with the immune_cell of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCL4L2-associated genes across cancer lineages are CD4+ T-cells and aDC. Each is linked with CCL4L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCL4L2-to-partner and partner-to-CCL4L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ T-cells grouped by CCL4L2-low versus CCL4L2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL4L2→partner) and Y-score (partner→CCL4L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECCD4+ T-cells →+0.007+5.258<.001.02931
UCECaDC →+0.114+2.818.011.03711
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

CD4+ T-cells by CCL4L2 expression — UCEC

Box plot of CD4+ T-cells in CCL4L2-low vs CCL4L2-high samples in UCEC.

Explore this box plot interactively →

Exploration