CCL28

Across TCGA patient cohorts, CCL28 mutation is significantly associated with the RNA expression of many other genes, with 40 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCL28-associated genes across cancer lineages are MIR6803, RNA5SP412, and LRRC30. Each is linked with CCL28 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCL28-to-partner and partner-to-CCL28 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6803 grouped by CCL28-low versus CCL28-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL28→partner) and Y-score (partner→CCL28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	MIR6803 →	+0.734	+5.733	<.001	.001	3	2
UCEC	RNA5SP412 →	+0.863	+3.382	<.001	.004	3	1
LUAD	LRRC30 →	+0.034	+7.930	<.001	.008	3	1
LUAD	MIR552 →	+0.286	+7.930	<.001	.008	3	1
LUAD	MCUR1P2 →	+0.064	+7.930	<.001	.008	3	1
UCEC	MIR4730 →	+1.111	+3.978	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

MIR6803 by CCL28 expression — LUSC

Explore this box plot interactively →