CCL28

Across TCGA cell cohorts, CCL28 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,181 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CCL28-associated GO terms across cancer lineages are Negative regulation of leukocyte tethering or rolling, Membrane assembly, and Membrane biogenesis. Each is linked with CCL28 in more than 16 cancer types. Because this analysis shows association rather than direction, both CCL28-to-partner and partner-to-CCL28 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of leukocyte tethering or rolling grouped by CCL28-low versus CCL28-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCL28→partner) and Y-score (partner→CCL28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Negative regulation of leukocyte tethering or rolling →	+1.624	+2.417	<.001	<.001	3	17
PANCREAS	Membrane assembly →	+0.109	+2.506	<.001	<.001	3	14
OESOPHAGUS	Membrane biogenesis →	+0.103	+1.641	.001	.003	2	12
LUNG_NSCLC_LUSC	Cytolysis in another organism →	+1.428	+1.838	.003	.002	2	11
BONE	Endosome to lysosome transport →	+0.055	+1.336	.001	.001	2	10
BONE	Actin filament organization →	+0.133	+1.726	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,181 associations by consensus.

Negative regulation of leukocyte tethering or rolling by CCL28 expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →